ARTICLE VI  

MALAYSIAN JOURNAL OF
NUTRITION
Official publication of the Nutrition Society of Malaysia

December 1999, Volume 5 No. 1&2

Mal J Nutr 5:55-59, 1999.
http://nutriweb.org.my/publications/mjn005/mjn5n12_006.pdf

The potential of the coelomic fluid in sea cucumber as an antioxidant

Hawa I, Zulaikah M, Jamaludin M, Zainal Abidin AA, Kaswandi MA and Ridzwan BH

Department of Biomedical Science, Faculty of Allied Health Sciences, Universiti Kebangsaan Malaysia, Jalan Raja Muda A. Aziz, 50300 K. Lumpur, Malaysia.

ABSTRACT   (Full Article)
In a biological system the product of free-radical induced-lipid peroxidation are conjugated dienes (CDs), lipid peroxides and malondialdehyde (MDA). Its control depends on antioxidant activities. Antioxidant defend the body system by controlling the damage caused by the free radicals. This paper describes lipid peroxidation process and antioxidant activities present in three species of holothuroid obtained from the coastal waters of Terengganu, Malaysia. Among the three species studied, the coelomic fluid of Bohadschia mamorata vitiensis contained the highest level of protein (7.24 + 0.04)g/L. The coelomic fluid of Stichopus badionotus Selenka contained the highest level of superoxide dismutase (SOD) (9.46 + 0.99)X 10⁵ IU/g protein, MDA (16.46 + 1.28)nmol/g protein and total antioxidant activities (AOA) (58.81 + 5.70) %. In Stichopus variegatus Semper the coelomic fluid only demonstrated the highest level of CDs (94.19 + 11.34) RU/g protein compared with the other two species. This preliminary study indicated that some form of antioxidant activities are present in the coelomic fluid of holothuroids.